As you probably know, effective ad placement is critical if you plan to make any significant amounts of money through Google Adsense 
or other contextual ad systems. Using a blog template with distinct ad blocks and optimized ad placements will very likely help you increase your Click through rates and affiliate conversions. These customized blog designs are also known as Adsense Ready themes.
How are Adsense Ready Themes different from other blog templates?
A key element that is central to all Adsense Ready themes is their focus on integrating contextual ads around content. As you will notice, the ads and link units are carefully placed above, beside and below each individual post to maximize exposure and their click through potential. 16 Adsense Optimized Wordpress Themes to Maximize your Contextual Ad Earnings